George IIexercised little control over British domestic policy, which was largely controlled by the Parliament of Great Britain. As elector, he spent twelve summers in Hanover, where he had more direct control over government policy.

During the War of the Austrian Succession, George participated at the Battle of Dettingen in 1743, and thus became the last British monarch to lead an army in battle. In 1745, supporters of the Catholic claimant to the British throne, James Francis Edward Stuart ("The Old Pretender"), led by James's son Charles Edward Stuart ("The Young Pretender" or "Bonnie Prince Charlie"), attempted and failed to depose George in the last of the Jacobite rebellions.

Spencer Compton, 1st Earl of Wilmington, KG, PC was a British Whig statesman who served continuously in government from 1715 until his death. He served as the Prime Minister from 1742 until his death in 1743. He is considered to have been Britain's second Prime Minister, after Sir Robert Walpole, but worked closely with the Secretary of State, Lord Carteret, in order to secure the support of the various factions making up the Government.

Henry Pelham was a British Whig statesman, who served as Prime Minister of Great Britain from 27 August 1743 until his death.

Pelham's premiership was relatively uneventful in terms of domestic affairs, although it was during his premiership that Great Britain experienced the tumult of the 1745 Jacobite uprising. In foreign affairs, Great Britain fought in several wars. Upon Pelham's death, his brother Newcastle took full control of the ministry.